In October 2024, scientists officially launched clinical trials for an experimental drug designed to stimulate the growth of new teeth in adults. Dr. Katsu Takahashi, the lead researcher of the project, described the technology as something completely different from traditional dental treatments.

The first phase of the trial involves 30 adult men aged between 30 and 64 who are missing at least one molar tooth. Researchers are investigating whether the medicine is safe and capable of reactivating the process of tooth regrowth.

The treatment works by blocking a protein called USAG-1, which normally prevents teeth from growing again after childhood. By disabling this protein, scientists hope the body will naturally regrow real teeth. Previous animal studies reportedly showed very promising results.

If successful, the next phase of the project will focus on children born with congenital anodontia, a rare condition in which teeth never fully develop.

Researchers believe this breakthrough could one day completely replace dentures and dental implants — and if the trials continue successfully, the treatment could become publicly available around 2030.