Comparison of the results of hematopoietic stem cell transplantation in children, allogeneic transplantation from fresh cell source with frozen (Cryopreserved)

Design and evaluation of anti-GD2 gamma delta CAR-T on a malignant neuroblastoma cell line

 Comparing the efficacy and side effects of Romiplostim in thrombocytopenia caused by thrombocytopenic purpura of the immune system and thrombocytopenia caused by other diseases in children

 Investigation of the safety of mesenchymal stem cells with the origin of menstrual blood in the treatment of grade IV GVHD resistant to steroids in children

Investigation of the level of toxicity of natural killer cells following inhibition of PD-1 and TIGIT receptors on AML cell line in laboratory conditions

 In vitro phase of SMN1 gene replacement in fibroblastic cells of a patient with SMA type I lacking SMN expression

 Making allogeneic platelet paste from umbilical cord blood and investigating its effect on treatment-resistant GVHD wounds of the oral cavity: a pilot clinical trial

Implementation of a phase one clinical trial using pseudo-memory NK cells along with determining the mismatch of KIR receptors from the second donor after haploidentical transplantation in children wi

 Investigating the therapeutic effect of Romiplostim in thrombocytopenia after hematopoietic stem cell transplantation in children

Evaluation of the efficacy of T-cell receptor-based therapy in neuroblastoma

Comparison of the results of hematopoietic stem cell transplantation in child patients who are candidates for allogeneic transplantation from fresh and cryopreserved cell sources

Beta thalassemia gene therapy (first phase): construction of efficient lentivirus construct carrying human beta globin gene and its transduction into CD34 stem cells isolated from thalassemia major patients

Evaluation of the effectiveness of ruxolotinib in treatment-resistant acute gastrointestinal GVHD after hematopoietic stem cell transplantation in children

Investigating the effect of cytomegalovirus infection and its treatment on the complications and outcome of transplantation after hematopoietic stem cell transplantation in children

Preclinical investigation of the effect of miR-326 and miR-328 on the expression of Genzyme B, perforin and the cytotoxic function of NK cells in Wilms tumor

Genetic modification of LAD-1 gene by high-fidelity CRISPR-Cas9 using HDR method in human hematopoietic stem cells (HSC)

Investigating factorsrelated to hemorrhagic cystitis and its prognosis after hematopoietic stem cell transplantation in children

 Implementation of a phase one clinical trial using pseudo-memory NK cells along with determining the mismatch of KIR receptors from the second donor after haploidentical transplantation in children with AML

 Evaluation of the effectiveness of ruxolotinib in treatment-resistant acute gastrointestinal GVHD after hematopoietic stem cell transplantation in children

 Investigating the effect of Plerixafor on the release of hematopoietic stem cells(+CD34) in children with neuroblastoma who are candidates for autologous hematopoietic stem cell transplantation

 Investigation of the relative frequency of acute kidney injury with urine NGAL and serum creatinine indicators in the diagnosis of acute kidney injury after hematopoieticstemcell transplantation in the children's medical center from March 2021 to March 2022

 Comparison of the prevalence of complications and prognosis of allogeneic hematopoietic stem cell transplantation before and after the COVID-19 pandemic (from September 2014 to March 2015) in Children's Medical Center

 Investigating survival rate and incidence of GVHD in children receiving T-globulin 25 as an immunosuppressive agent during hematopoietic stem cell transplantation